Clinical significance of serum guanase activities determined by ammonia method using 8-azaguanine as substrate
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چکیده
منابع مشابه
buckling of viscoelastic composite plates using the finite strip method
در سال های اخیر، تقاضای استفاده از تئوری خطی ویسکوالاستیسیته بیشتر شده است. با افزایش استفاده از کامپوزیت های پیشرفته در صنایع هوایی و همچنین استفاده روزافزون از مواد پلیمری، اهمیت روش های دقیق طراحی و تحلیل چنین ساختارهایی بیشتر شده است. این مواد جدید از خودشان رفتارهای مکانیکی ارائه می دهند که با تئوری های الاستیسیته و ویسکوزیته، نمی توان آن ها را توصیف کرد. این مواد، خواص ویسکوالاستیک دارند....
Colorimetric determination of serum guanase activity.
A colorimetric method for the determination of serum guanase has been developed whereby ammonia, formed by the deamination of guanine, is measured by the phenatehypochlorite reaction. Variations in substrate concentration, time of incubation, pH, temperature, and concentration of enzyme have been investigated with respect to enzyme activity. The determination of serum guanase appears to be usef...
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The biochemical mechanism underlying the cytotoxic and carcinostatic (l-3) effects of 8-axaguanine is still uncertain. Current hypotheses are that the compound acts directly as a metabolite antagonist to guanine utilization (4) or that it is incorporated into nucleic acids and that these fraudulent nucleic acids serve as the active pharmacological agents (5-7). An alternative hypothesis being e...
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In the process of studying conventional methods for differentiation of mycobacteria, a number of compounds were tested in this laboratory. Among them, hydroxylamine and 8-azaguanine were found to be useful. Among slowly growing mycobacteria, Mycobacterium tuberculosis and 11. bovis were distinguished from others by their sensitivity to both compounds; among rapidly growing mycobacteria, fortuit...
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ژورنال
عنوان ژورنال: Kanzo
سال: 1975
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.16.10